Titlebook: Clinical Cases in Melanoma; Torello Lotti,Michael Tirant,Uwe Wollina Book 2020 The Editor(s) (if applicable) and The Author(s), under excl

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Serious Adverse Event Caused by Combined Target Therapy,ommonly causes a wide spectrum of adverse events, they are usually manageable. Toxic epidermal necrolysis represents severe mucocutaneous reaction, usually triggered by medications. Here we present a first case of toxic epidermal necrolysis induced by combined target therapy (vemurafenib plus cobime

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A Growing Mass in the Left Foot, 4-year evolution with a small black “nevus”. One year before the consultation, the lesion started growing, with occasional bleeding and pain. The patient had lost 7 kg of non-intentional body weight during the last 3 months.

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,Clinical and Dermoscopic Simulators of Melanoma: Pigmented Bowen’s Disease, macule with uneven borders and 1.2 cm of maximum diameter was observed (Fig. 11.1). Dermoscopy disclosed central hypopigmentation surrounded by multiple, peripheral black dots with a linear fashion arrangement and confluent structureless brown areas (Fig. 11.2). After clinical and dermoscopic corre

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