Titlebook: Clinical Application of Radiolabelled Platelets; Ch. Kessler,M. R. Hardeman,J.-N. Petrovici Book 1990 Kluwer Academic Publishers 1990 Scin

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Tc-99m-Labeled Autologous Platelets as Screening in Patients with Cerebrovascular Diseaseradiator, Tc-99 m-phytate, in the detection of atherosclerotic lesions, using a large collective of patients with cerebrovascular diseases as test group. Tc-99 m-phytate has the advantage of having a lower radiation load than indium-111 and is also not as expensive.

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Platelet Isolation Technique and Viability Testing1] or simply designated as “blood dust”, as Page [2] had been taught. The name “thrombocyte”, first proposed by the Dutch Scientist Dekhuyzen [3], was initially used for the nucleus-containing platelet found in sub-mammalian species but was later accepted also for the nucleus-lacking mammalian platelets.

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Imaging Thrombus with Radiolabelled Monoclonal Antibody to Plateletsmaking use of this technique. Oster et al have demonstrated the possibility of labelling platelets by the use of a radiolabelled monoclonal antibody in the dog and we have recently explored this technique in man.

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Monitoring of Antithrombotic Therapy with Radiolabelled Platelets1) and got even more importance after the discovery of prostacyclin (prostaglandin (PG) 12) by Sir John Vane, Moncada and other (36). They claimed an important role in hemostasis via an action of platelet-cAMP (4) and a decreased in-vitro PG12-formation by the arterial wall in atherosclerosis (50).

Stress

Book 1990s detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its phy

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https://doi.org/10.1057/97811375490201] or simply designated as “blood dust”, as Page [2] had been taught. The name “thrombocyte”, first proposed by the Dutch Scientist Dekhuyzen [3], was initially used for the nucleus-containing platelet found in sub-mammalian species but was later accepted also for the nucleus-lacking mammalian platelets.

Conscientious

Management of Financial Stability Risk,making use of this technique. Oster et al have demonstrated the possibility of labelling platelets by the use of a radiolabelled monoclonal antibody in the dog and we have recently explored this technique in man.

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