Titlebook: Chromosomal Translocations and Genome Rearrangements in Cancer; Janet D. Rowley,Michelle M. Le Beau,Terence H. Rab Book 2015 Springer Inte

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https://doi.org/10.1007/978-3-319-19983-2Cancer genomes; Chromosomal abnormalities; Chromosomal translocations; Genome rearrangement; Somatic mut

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978-3-319-79292-7Springer International Publishing Switzerland 2015

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From Social Protection to Social Commons,rom single nucleotide changes to those involving parts of chromosomes or whole chromosomes, likely reflect the many different solutions taken by individual tumours to escape normal growth regulatory mechanisms. A variety of molecular and cytogenetic techniques, differing in resolution and capabiliti

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Redefining the Agenda for Social Justicerrent chromosomal translocations are found in various cancers. Recently developed high-throughput approaches to clone genome-wide translocations that involve site-specific DSBs have provided new insights into mechanisms of chromosomal translocations. Such studies confirmed that, beyond cellular sele

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https://doi.org/10.1057/9780230554689s that partially inhibit DNA synthesis, inducing replication stress. The common fragile sites (CFS) are numerous in the human genome, and are essentially observed in all individuals. Although the molecular basis for chromosome fragility of CFSs remains incompletely understood, there is now general a

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