Titlebook: Chromosomal Alterations; Methods, Results and Günter Obe,Vijayalaxmi Book 2007 Springer-Verlag Berlin Heidelberg 2007 Aberrationen, chromos

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Book 2007dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer are topics discussed in this book. The book will help the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discusse

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Red Cell Structure and Its Breakdown,he culture medium. In this chapter we review the evidence for targeted and non-targeted induction of chromosomal rearrangements after exposure to ionizing radiation and speculate about potential mechanisms and their significance in radiation risk assessment.

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Sister-Chromatid Exchanges,n culture do not grow in a synchronized manner, perturbations of the cell cycle kinetics provide a potential source of error in estimating the true SCE frequency. The aim of this chapter is to discuss some problems of the SCE assay, especially those related to the use of BrdU.

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s and as a predictive measure of cancer.Written by respected.Cytogenetics is a very important research tool in basic and applied research. The uses of cytogenetics in human-population monitoring, in biological dosimetry in radiation accidents and in astronauts and as a predictive measure of cancer a

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DNA Lesions Induced by Ionizing Radiation,amaged DNA sites, predominantly damaged bases, single-stand breaks, double-strand breaks and DNA–protein cross-links. Molecular oxygen enhances and thiols reduce the severity of the DNA damage. The mechanisms leading to these lesions are discussed in the light of our present knowledge of the underlying free-radical chemistry.

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