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Titlebook: Chromatin Architecture; Advances From High-r Kirti Prakash Book 2017 Springer International Publishing AG 2017 Superresolution Microscopy.S

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發(fā)表于 2025-3-21 20:05:31 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Chromatin Architecture
副標(biāo)題Advances From High-r
編輯Kirti Prakash
視頻videohttp://file.papertrans.cn/227/226295/226295.mp4
概述Nominated as an outstanding PhD thesis by the Institute of Molecular Biology, Mainz, and Heidelberg University, Germany.Provides a pictorial description of super-resolution microscopy and chromatin ar
叢書名稱Springer Theses
圖書封面Titlebook: Chromatin Architecture; Advances From High-r Kirti Prakash Book 2017 Springer International Publishing AG 2017 Superresolution Microscopy.S
描述.This book sheds new light on the current state of knowledge concerning chromatin organization. Particular emphasis is given to the new imaging potential offered by super-resolution microscopy, which allows DNA imaging with a very high labeling density..From the early work on chromosomes by Walther Flemming in the nineteenth century to recent advances in genomics, the history of chromatin research now spans more than a century. The various milestones, such as the discovery of the double helix structure, the sequencing of the human genome, and the recent description of the genome in 3D space, show that understanding chromatin and chromosome function requires a clear understanding of its structure..Presenting cutting-edge data from super-resolution single molecule microscopy, the book demonstrates that chromatin manifests several levels of folding, from nucleosomes to chromosomes. Chromatin domains emerge as a new fundamental building block of chromatin architecture, with functions possibly related to gene regulation..A detailed description of chromatin folding in the pachytene stage of meiosis serves as a model for exploring this functionality, showing the apparent interplay between
出版日期Book 2017
關(guān)鍵詞Superresolution Microscopy; Single Molecule Localisation Microscopy; Genome Architecture; Chromatin Dom
版次1
doihttps://doi.org/10.1007/978-3-319-52183-1
isbn_softcover978-3-319-84841-9
isbn_ebook978-3-319-52183-1Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-21 21:53:13 | 只看該作者
Conclusions,n effort to combine and synchronise observations from different studies on chromatin organisation was lacking. This thesis is an attempt to combine old and new evidence to understand various structure-function conundrums of chromatin organisation and understand how chromatin structure affects gene regulation.
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發(fā)表于 2025-3-22 02:45:24 | 只看該作者
2190-5053 description of super-resolution microscopy and chromatin ar.This book sheds new light on the current state of knowledge concerning chromatin organization. Particular emphasis is given to the new imaging potential offered by super-resolution microscopy, which allows DNA imaging with a very high labe
地板
發(fā)表于 2025-3-22 06:27:23 | 只看該作者
https://doi.org/10.1007/978-3-030-30004-3. of diameter for the nucleus) the entire genome, which is billions of base pairs long and roughly 3?m in length when completely unfolded. Moreover, information needs to be retrieved from this highly condensed structure when a gene needs to be expressed at a fast pace.
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發(fā)表于 2025-3-22 09:11:36 | 只看該作者
Structure, Function and Dynamics of Chromatin,. of diameter for the nucleus) the entire genome, which is billions of base pairs long and roughly 3?m in length when completely unfolded. Moreover, information needs to be retrieved from this highly condensed structure when a gene needs to be expressed at a fast pace.
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發(fā)表于 2025-3-23 02:54:22 | 只看該作者
Periodic and Symmetric Organisation of Meiotic Chromosomes,ne chromosomes. DNA is found to be non-randomly distributed along the length of chromosome proteinaceous backbone, the synaptonemal complex (SC), in condensed clusters. Furthermore, chromatin is organized in spatially distinct functional clusters associated to specific epigenetic marks (Fig.?.).
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發(fā)表于 2025-3-23 09:04:00 | 只看該作者
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