| 書目名稱 | Cholesterol and PI(4,5)P2 in Vital Biological Functions | | 副標(biāo)題 | From Coexistence to | | 編輯 | Avia Rosenhouse- Dantsker | | 視頻video | http://file.papertrans.cn/227/226164/226164.mp4 | | 概述 | Provides a comprehensive overview of the current knowledge of the interplay between cholesterol and PI(4,5) P2.Provides an overview of the emerging relationship between cholesterol and PI(4,5).Discuss | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | .Cholesterol is an essential component of the plasma membrane. Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P.2.), although a minor phospholipid, is the most abundant membrane phosphoinositide. Both lipids play key roles in a variety of cellular functions including as signalling molecules and major regulators of protein function. Studies on these important lipids have traditionally focused on the effect of each lipid individually. Accumulating evidence indicates, however, that these lipids may cross-regulate each other’s levels. Furthermore, it is becoming evident that cholesterol and PI(4,5)P.2. can act together to modulate protein function and biological processes. ..This book provides an overview of cellular functions and molecular mechanisms in which cholesterol and PI(4,5)P.2. functions extend from parallel existence to crosstalk. It includes four sections. The first section introduces the reader to cholesterol and PI(4,5)P.2.. The second section demonstrates the mutual influence of these two critical lipids on their levels. The third section, divided into two parts, describes the co-modulation of protein function by cholesterol and PI(4,5)P.2.. The first part focuses on ion | | 出版日期 | Book 2023 | | 關(guān)鍵詞 | lipid transfer proteins; cholesterol depletion; PI(4,5)P2; protein function; human disorders; plasma memb | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-031-21547-6 | | isbn_ebook | 978-3-031-21547-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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