Titlebook: Chemotherapy of Viral Infections; Paul E. Came,Lawrence A. Caliguiri Book 1982 Springer-Verlag Berlin Heidelberg 1982 Arzneitherapie.Infec

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Immunotherapy and Immunoregulationeen recognized for centuries. In eighteenth century Europe, variolation was practiced as a crude form of immunization to protect against smallpox. This eventually led to Jenner’s acclaimed experiments in which he successfully used vaccine for the first time, employing a “l(fā)ive, attentuated virus” for

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Guanidinenitial discovery, mutants that were either resistant to or dependent upon guanidine were described (. et al. 1963; . et al. 1963). In general, growth of many members of the Picornaviridae family, which comprises a large number of lipid-free animal viruses that contain single-stranded RNA genomes, is

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BIBLE

Arildone: A ,-Diketoneiral activity with promising results. One of these compounds, arildone, was extensively studied and shown to be active against a wide variety of DNA and RNA viruses in vitro. In addition, arildone was shown to be effective against herpesvirus infections in vivo. Arildone and its metabolites were wel

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Rifamycinsa an aliphatic ansa chain. Originally, a mixture of five compounds, designated rifamycins A–E, was isolated from the fermentation broth of . (. et al. 1959 a, b). It was subsequently found that one of the compounds, rifamycin B, was produced almost exclusively when sodium diethylbarbiturate was pres

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0171-2004 the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other discipline

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