Titlebook: Chemosensitivity Testing in Oncology; Uwe Reinhold,Wolfgang Tilgen Conference proceedings 2003 Springer-Verlag Berlin Heidelberg 2003 brea

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0080-0015 otherapy agents. The idea was to eliminate ineffective agents and unnecessary toxic treatment while selecting drugs active in vitro or in the mouse model that might increase the probability of response in the patient. None of these test models, however, achieved routine clinical application in the p

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https://doi.org/10.1007/978-1-349-04806-9 out of 18 assays (72%) the specific anticancer drug being tested induced . transcription. No decrease in . mRNA concentration was observed. Our data suggest that . induction by antineoplastics is one of the reasons for failure of ovarian cancer therapy but may vary individually.

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