Titlebook: Chemokine Roles in Immunoregulation and Disease; P. M. Murphy,R. Horuk Conference proceedings 2004 Springer-Verlag Berlin Heidelberg 2004

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Chemokine Influences on Adaptive Immunity and Malignancies of the Immune System,s, over 40 distinct human chemokines have been identified (Rossi and Zlotnik 2000). In general, chemokine number and diversity increase as organisms climb the evolutionary ladder, suggesting that this protein family evolved pari passu with specialized leukocyte subtypes in order to control their spe

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Preliminary Observations on CC Chemokine Receptor Expression by Mononuclear Phagocytes in Multiple n inflammation and physiological function of the immune system, by modulating biological responses, including migration, enzyme secretion, cellular adhesion, cytotoxicity, tumor cell growth, degranulation, and T-cell activation (MacKay 2001; Asensio and Campbell 1999; Gerard and Rollins 2001). Chemo

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Regulation of Eosinophil Trafficking in Asthma and Allergy,onstitute 1%–2% of circulating leukocytes. However, a large proportion of the eosinophils of the body are resident in walls of the gastrointestinal tract. The bone marrow also contains a reserve of immature and mature eosinophils. Eosinophils are thought to have evolved as effector cells in host def