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Titlebook: Chemical Epigenetics; Antonello Mai Book 2020 Springer Nature Switzerland AG 2020 Epigenetic targets.HDAC inhibitors.cyclic peptides.SIRT

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發(fā)表于 2025-3-21 17:19:32 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Chemical Epigenetics
編輯Antonello Mai
視頻videohttp://file.papertrans.cn/225/224329/224329.mp4
概述Offers a comprehensive review of the chemical mechanisms involved in epigenetics.Covers the significant findings about epigenetic targets.Explores the design, synthesis and biological validation of ep
叢書(shū)名稱Topics in Medicinal Chemistry
圖書(shū)封面Titlebook: Chemical Epigenetics;  Antonello Mai Book 2020 Springer Nature Switzerland AG 2020 Epigenetic targets.HDAC inhibitors.cyclic peptides.SIRT
描述.This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. . .This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.?.
出版日期Book 2020
關(guān)鍵詞Epigenetic targets; HDAC inhibitors; cyclic peptides; SIRT inhibitors; Lysine Methyltransferases; Arginin
版次1
doihttps://doi.org/10.1007/978-3-030-42982-9
isbn_softcover978-3-030-42984-3
isbn_ebook978-3-030-42982-9Series ISSN 1862-2461 Series E-ISSN 1862-247X
issn_series 1862-2461
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

書(shū)目名稱Chemical Epigenetics影響因子(影響力)




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Extreme Values and LIL Behavior,for studying HAT biology. In the present chapter, the main features of HAT enzymes and related diseases have been summarized, with a particular focus on HATi, analysing their structure-activity relationships, mechanisms of action and potential therapeutic applications.
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Some recent results on empirical processes,2). As LSD1/2 are involved in various diseases, their inhibitors are considered useful not only as a chemical tool for probing the biology of LSD1/2 but also as therapeutic agents. In this chapter, the biology, pharmacology, and inhibitors of LSD1/2 are presented, and the potential of LSD inhibitors as therapeutic agents is discussed.
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Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors,for studying HAT biology. In the present chapter, the main features of HAT enzymes and related diseases have been summarized, with a particular focus on HATi, analysing their structure-activity relationships, mechanisms of action and potential therapeutic applications.
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