Titlebook: Changing Paradigms in the Management of Breast Cancer; Marissa Howard-McNatt Book 2018 Springer International Publishing AG 2018 Breast Im

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https://doi.org/10.1007/978-0-230-62911-0that these molecular drivers are ubiquitous in all subtypes of breast cancer has resulted in a paradigm shift away from focusing on traditional targets, such as the estrogen receptor or HER2 receptor, to blocking oncogenic signaling pathways, cell-cycle regulatory checkpoints, or epigenetic modulato

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https://doi.org/10.1007/978-0-230-62911-0breast cancer prediction for the subset of individuals with heritable disorders. Genetic testing for hereditary syndromes can aid in early detection and prevent cancer through screening, surgical prophylaxis, and chemoprevention. Genetic risk prediction can improve survival when combined with early

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https://doi.org/10.1007/978-0-230-62911-0clude genetic evaluation for cancer predisposing mutations, fertility preservation, and psychosocial issues. The constellation of all of these factors make younger patients with breast cancer require a multidisciplinary team.

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