Titlebook: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines; Larry J. Anderson,Barney S. Graham Book 2013 The Editor(s) (if appl

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,Das Konfliktgespr?ch: Wie l?sen wir es?,use vaccine-associated enhanced RSV disease; (2) they broadly stimulate innate, humoral, and cellular immunity, both systemically and locally in the respiratory tract; (3) they are delivered intranasally; and (4) they replicate in the upper respiratory tract of young infants despite the presence of

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Absprachen: Wie setzen wir es um?,op a licensed vaccine is not due to lack of effort, as numerous vaccine candidates have been characterized in preclinical and clinical studies spanning five decades. The vaccine candidates thus far explored can be generally divided into four categories: (1) whole inactivated virus, (2) replication c

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https://doi.org/10.1007/978-3-642-38919-1Epidemiology; Pathogenesis; RSV; Virology; Virus infection; vaccines; infectious diseases

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978-3-662-52155-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE

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C. Br?hler,V. Weiss,W. Meyh?fertment of immune cells as well as promote anti-viral responses. In this review, we summarize the results of numerous studies that have characterized the innate immune responses that contribute to the RSV-induced responses and may be important considerations for the development of efficacious vaccine strategies.

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https://doi.org/10.1007/978-3-540-48845-3ene discovery and transcriptome profiling for respiratory syncytial virus (RSV) are discussed in the context of biological relevance for disease intervention in the clinical setting and vaccine development.

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Respiratory Syncytial Virus and Reactive Airway Diseasegesting that instead of being causal, severe RSV infection may instead be a marker of a predisposing factor for asthma. In this chapter, we will explore the evidence that RSV infection leads to RAD in infants and adults, and how these different forms of RAD may be linked.

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Innate Immune Responses to Respiratory Syncytial Virus Infectiontment of immune cells as well as promote anti-viral responses. In this review, we summarize the results of numerous studies that have characterized the innate immune responses that contribute to the RSV-induced responses and may be important considerations for the development of efficacious vaccine strategies.