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Titlebook: Centromeres and Kinetochores; Discovering the Mole Ben E. Black Book 2017 Springer International Publishing AG 2017 centomeres.kinetochores

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發(fā)表于 2025-3-21 20:03:09 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Centromeres and Kinetochores
副標(biāo)題Discovering the Mole
編輯Ben E. Black
視頻videohttp://file.papertrans.cn/224/223231/223231.mp4
概述Presents the latest advances concerning the regulation of chromosome segregation during cell division.Covers state-of-the-art techniques employed in the field.Incorporates a wealth of different model
叢書名稱Progress in Molecular and Subcellular Biology
圖書封面Titlebook: Centromeres and Kinetochores; Discovering the Mole Ben E. Black Book 2017 Springer International Publishing AG 2017 centomeres.kinetochores
描述.This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores. The authors cover both state-of-the-art techniques and a range of species and model systems, shedding new light on the molecular mechanisms controlling the transmission of genetic material between cell divisions and from parent to offspring.?.The chapters cover five major areas related to the current study of centromeres and kinetochores: 1) their genetic and epigenetic features, 2) key breakthroughs at the molecular, proteomic, imaging and biochemical level, 3) the constitutive centromere proteins, 4) the role of centromere proteins in the physical process of chromosome segregation and its careful orchestration through elaborate regulation, and 5) intersections with reproductive biology, human health and disease, as well as chromosome evolution. The book offers an informative and provocative guide for newcomers as wellas those already acquainted with the field..
出版日期Book 2017
關(guān)鍵詞centomeres; kinetochores; chromatin; chromosome segregation; epigenetics; mitosis; Cell Cycle Analysis
版次1
doihttps://doi.org/10.1007/978-3-319-58592-5
isbn_softcover978-3-319-86436-5
isbn_ebook978-3-319-58592-5Series ISSN 0079-6484 Series E-ISSN 2197-8484
issn_series 0079-6484
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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沙發(fā)
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發(fā)表于 2025-3-22 01:36:09 | 只看該作者
The Power of , Egg Extract for Reconstitution of Centromere and Kinetochore Functiontro reconstitution studies are beginning to uncover how the kinetochore is assembled upon the underlying centromere, how the kinetochore couples chromosome movement to microtubule dynamics, and how cells ensure the site of kinetochore assembly is maintained from one generation to the next. Here we g
地板
發(fā)表于 2025-3-22 06:46:14 | 只看該作者
Centrochromatin of Fungile microtubules during chromosome segregation. Research over the last decades demonstrated that centromeres are defined by a combination of genetic and epigenetic factors. Recent work showed that centromeres are quite diverse and flexible and that many types of centromere sequences and centromeric c
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發(fā)表于 2025-3-22 12:05:44 | 只看該作者
Evolutionary Lessons from Species with Unique Kinetochoresnt to spindle microtubules. Kinetochore research over the last several decades has been focused on a few animal and fungal model organisms, which revealed a detailed understanding of the composition and organization of their kinetochores. Yet, these traditional model organisms represent only a small
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發(fā)表于 2025-3-22 16:20:38 | 只看該作者
Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to t of a strong self-templating epigenetic mechanism that renders centromeres heritable. We review how specific quantitative microscopy approaches have contributed to the determination of the copy number, architecture, size, and dynamics of centromeric chromatin and its associated centromere complex a
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發(fā)表于 2025-3-22 20:34:45 | 只看該作者
Orchestrating the Specific Assembly of Centromeric Nucleosomescanonical histone H3 variant is replaced by Centromere Protein A (CENP-A). Therefore, the assembly and propagation of centromeric nucleosomes are critical for maintaining centromere identify and ensuring genomic stability. Centromeres direct chromosome segregation (during mitosis and meiosis) by rec
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Centromere Silencing Mechanismses as the site of centromere formation and kinetochore assembly. Decades of research have defined the DNA sequence and protein components of functional centromeres, and the interdependencies of specific protein complexes for proper centromere assembly. Less is known about how centromeres are disasse
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