Titlebook: Cellular and Molecular Approaches to Regeneration and Repair; Paul A. Lapchak,John H. Zhang Book 2018 Springer International Publishing AG

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The Combination of Stem Cell Factor (SCF) and Granulocyte-Colony Stimulating Factor (G-CSF) in Repaieloping a pharmaceutical approach to enhance brain repair and improve functional outcomes post-acute stroke is a very important but less investigated area in stroke research. Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are the well-characterized vital hematopoietic growt

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Mesenchymal Stromal Cell Therapy of Stroke for stroke has been a target of intense research. Accumulating preclinical literature has identified that bone marrow mesenchymal stromal cell (MSC) treatment of stroke improves neurological functional outcome after stroke. This chapter focuses on the therapeutic effects and molecular mechanisms un

GLOOM

Combination Treatment of Mesenchymal Stem Cells (MSCs) and Angelica sinensis’ Active Ingredients fortudies reported that Angelica (also called Dong quai, a well-known Chinese herbal medicine) extracts and its active ingredients such as ligustilide, n-Butylphthalide and sodium ferulate had significant effects of anti-inflammatory, anti-activation of oxygen free radicals, angiogenesis, anti-platelet

Gerontology

PANT

SB623 Preclinical and Clinical Trial Experiencere are nearly 800,000 strokes annually, and over seven million individuals (approximately 3% of the adult population) live with the sequelae of a prior stroke [2]. More than half of these individuals suffer from long-term limitation of functional mobility [3]. From an economic perspective, the direc

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Preparing for Future Stem Cell Clinical Trialsnt control groups, and typically with wide treatment time windows and clinical entry criteria. Only recently have trials begun to consider the evolving preclinical evidence base and strategies that might translate this successfully into clinical use. The next few years will witness clinical trials t

Ventilator

Extra-Cellular Vesicles: A Promising Approach for Translating Cell-Based Therapyvestigation and are being investigated in greater depth. It is becoming increasingly clear that one of the main ways that cell therapies based on mesenchymal stem cells (MSC) and other cells impart functional benefits to animals is through release of exosomes and other extracellular vesicles .. Moun

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Exosome and MiRNA in Strokewn promising potential. The principal mechanism of therapeutic action has been partially ascribed to their strong paracrine capacity. Exosomes are small vesicles released from all kinds of cells and mediate intercellular communication by transferring exosomal protein and microRNA (miRNA) cargoes bet

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