Titlebook: Cellular Function and Metabolism; Yoshio Yazaki (Professor of Medicine),Seibu Mochiz Book 1993 Springer Science+Business Media Dordrecht 1

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Ischemic changes in myocardial ionic eontents of the isolated perfused rat hearts as studied by NMRbserved in association with a second increase in Pi. This was accompnanied by an abrupt rise of the ventricular end-diastolic pressure. As there was a depletion of ATP at this time, the increase in intracellular Na. and associated decrease in intracellular K. may be explained by inhibition of the Na