Titlebook: Cellular Drug Delivery; Principles and Pract D. Robert Lu,Svein ?ie Book 2004 Springer Science+Business Media New York 2004 biology.cancer.

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Targeted Drug Delivery to Tumor Cells Using Colloidal Carriersanticancer drugs and genes. Tumors are an uncontrolled mass of proliferations of a single malignant cell arising from mutations, which are either inherited or caused by environmental factors .. In order to reach the tumor cells, systemically administered drugs have to overcome a number of obstacles,

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Biological Protein Nanostructures and Targeted Drug Deliverylar complexes or organelles within a cell while avoiding drug loading in nontargeted cells. Targeted delivery of drugs to specific cells involves the specific interactions between drugs or drug carriers and the cell-surface proteins through ligand—receptor interactions or antigen—antibody interactio

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Formulation Considerations for DNA-Based Therapeuticscurrently considered incurable, e.g., cancer, cystic fibrosis (CF), severe combined immunodeficiency (SCID), and acquired immune deficiency syndrome (AIDS) .. Considering the tremendous promise of DNA-delivery technology, in addition to the extensive genetic information now available from the Human

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Cationic Microparticles and Emulsions As Effective Delivery Systems for Immune Stimulatory CpG DNAeviously .. However, the particles used in early studies were nondegradable and therefore, were not appropriate for development as vaccine adjuvants for human use. In addition, antigens were often chemically conjugated to the nondegradable particles, adding an extra level of complexity and making co

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Mechanics

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https://doi.org/10.1007/978-3-322-97110-4e of the global market has been more than 10%. The large market size allows big pharmaceutical companies to invest heavily in research and development (R&D). In 2002 alone, the combined R&D budget of Pfizer, Pharmacia, Merck, Eli Lilly, and Bristol-Myers Squibb was more than $16 billion. Despite an

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Die Darstellung organisierter Interessenal active ingredients to elucidating the biological mechanisms of site-specific interactions, the science of cellular drug delivery is a complex, integral part of the treatment and prevention of life-threatening illnesses. Every year, new information is made available from many different research ar

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