Titlebook: Cell and Gene Therapies; Miguel-Angel Perales,Syed A. Abutalib,Catherine Bo Book 2019 Springer Nature Switzerland AG 2019 Chimeric antigen

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Old Age in Nineteenth-Century Irelandnormal and fully functional NK cells that are less inhibited by patient tumor. Despite these encouraging findings, NK cell therapy is limited by the lack of antigen specificity and by tumor escape likely resulting from the formation of a complex network of suppressive components in the tumor microen

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https://doi.org/10.1057/978-1-137-58714-5n their own class I MHC molecules to autologous T cells regardless of the MHC alleles expressed by the antigen source. When compared with other APCs, like macrophages, DCs are much more efficient and can elicit responses from very low numbers of T cells. In this chapter we review such and other mech

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