Titlebook: Cell Substrates; Their Use in the Pro John C. Petricciani,Hope E. Hopps,Paul J. Chapple Book 1979 The Editor(s) (if applicable) and The Aut

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because the production of a biological by plant cell cultures on commercial scale may be operational within five years. The primary purpose of this chapter is to review the current state of knowledge of plant cell culture as it bears on the production of biologicals.

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xciting new technologies and their obvious- utilities. Speakers and discussants led us onto a mountain of expectation. They portrayed the possibilities and probabilities of cell substrates capable of making vaccines and other biologicals more precise and of higher quality than would otherwise be possible.

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not discussed. Issues of benefits and risks have been discussed in the present symposium in the preceding paper (2). In the present paper, we would like to stress the need for quantitative data related to genetic and presumably nongenetic alterations in various cell substrates. These changes may oc

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ated eggs or CNS tissue from intact hosts. However, except for Dr. Netter who provided a review of recommendations and WHO requirements for producing inactivated viral vaccines in diploid cell lines, the speakers extended the scope of their presentations substantially beyond that defined by the sess