Titlebook: Cell Death; Mechanism and Diseas Hao Wu Book 2014 Springer Science+Business Media New York 2014 Apoptosis.Cell death.Receptors

懶鬼才會(huì)衰弱

Maria Renata da Cruz Duran,Adnan Qayyumed cell death can lead to developmental defects, neuropathies, infections, and cancer. Inhibitor of apoptosis (IAP) proteins are evolutionarily conserved regulators of cell death with impact on numerous cellular processes. Initially identified as inhibitors of cell death during viral infection, IAP

IRS

Maria Renata da Cruz Duran,Adnan Qayyumment of novel treatments. A cancer is a clonally related population of cells that persists, in part, because cells with altered DNA have been able to survive. It follows that genetic mutations that prevent a cell from killing itself are likely to promote the development of cancer. On the other hand,

倒轉(zhuǎn)

Maria Renata da Cruz Duran,Adnan Qayyumesponse (DDR) is a highly coordinated signaling pathway that functions to detect and repair DNA damage in cells, inhibiting transformation. However, when DNA damage is so severe that it cannot be repaired, the DDR promotes apoptosis, thus preventing the propagation of abnormal cells. The tumor suppr

BRUNT

https://doi.org/10.1007/978-981-13-0469-9roperly organized nervous system during development. However, unlike most other cell types, neurons must survive for the lifetime of the organism and therefore possess multiple, unique ways to tightly regulate cell death pathways. Neurons employ several distinct “brakes” within the apoptotic pathway

護(hù)航艦

Jyotiranjan Nayak,Sasmita Mishraf building blocks of cellular structures such as lipid membranes, proteins, and nucleic acids. In contrast, nutrient excess can increase ER stress and reactive oxygen species, leading to cellular damage and apoptosis. In this chapter, we detail three important aspects of the interplay between metabo

明確

,Vasoproliferative Tumors of the?Retina,ers necrosis in response to TNF-like death cytokines, certain toll-like receptors, and in response to viral pathogens was described. Signaling adaptors that contain the RIP homotypic interaction motif (RHIM), such as receptor interacting protein kinase (RIPK) 1 and RIPK3, are key inducers for this f

一起平行

混合

Ning Fan,Xuyang Liu,Jiantao Wangis. Here we review the structural information on DR signaling accumulated in the past decade and more. These studies highlight the assembly of oligomeric death domain superfamily complexes in caspase activation in apoptosis and the assembly of a functional amyloid complex in kinase activation in nec

carbohydrate

https://doi.org/10.1007/978-1-4614-9302-0Apoptosis; Cell death; Receptors

Archipelago

978-1-4939-4325-8Springer Science+Business Media New York 2014