Titlebook: Cell Cycle Inhibitors in Cancer Therapy; Current Strategies Antonio Giordano,Kenneth J. Soprano Book 2003 Springer Science+Business Media N

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Lucinda Backwell,Francesco d’Erricoastic period. The goal of chemopreventive drug development is to identify safe and effective chemopreventive agents for clinical use .. Agents with chemopreventive potential are tested in preclinical toxicity and pharmacokinetic studies and then moved forward to Phase I, II, and III clinical trials

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https://doi.org/10.1007/978-94-024-2115-6atic cells. The genetic defects associated with the process of tumor progression affect control of proliferation, programmed cell death (or apoptosis), cell-aging, angiogenesis, escape from immune response, and invasion and metastasis (.). These characteristics of tumor cells are to be considered as

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https://doi.org/10.1007/978-94-6091-385-3lopment of mechanism-based therapeutics. Compounds are becoming available that target almost every key regulator that governs the entry into S phase and mitosis: from growth factors to cyclin-dependent kinases. Given the increasing number of experimental therapeutic compounds, I will limit the discu

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Antonio Giordano,Kenneth J. SopranoIncludes supplementary material:

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