Titlebook: Cell Biology and Translational Medicine, Volume 16; Stem Cells in Tissue Kursad Turksen Book 2022 The Editor(s) (if applicable) and The Aut

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Identification of Small Molecules That Enhance the Expansion of Mesenchymal Stem Cells Originating ined from a variety of tissue types, including umbilical cord, adipose tissue, dental tissue, and bone marrow (BM). BM-MSCs are challenging in terms of their ex vivo expansion capability. Thus, we aimed to improve the expansion of BM-MSCs with small molecule treatments. We tested about forty small m

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,Human-Induced Pluripotent Stem Cell–Based Models for Studying Sex-Specific Differences in Neurodegeare sex-biased. It has long been suggested that biological sex differences are crucial for neurodegenerative diseases; however, how biological sex affects disease initiation, progression, and severity is not well-understood. Sex is a critical biological variable that should be taken into account in

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,Current Status, Barriers, and Future Directions for Humanized Mouse Models to Evaluate Stem Cell–Baents in glycemic control, reductions in insulin doses, and near-complete abrogation of severe hypoglycemia. Unfortunately, access to ITx remains limited by immunosuppression requirements and donor supply. Discovery of stem cell–derived functional islet-like clusters with the capacity to reverse diab

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An Overview of Zebrafish Modeling Methods in Drug Discovery and Development,eir relative genetic, molecular, physiological, and even anatomical similarities to humans, can provide a suitable platform for unraveling the mechanisms underlying human diseases and discovering new therapeutic approaches as well. Recently, zebrafish has attracted attention as a valuable experiment

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https://doi.org/10.1007/978-94-009-4968-3 of tissue damages and various diseases. Here, the most frequently applied and newly developed stem cell–based techniques are designated, and recent MSC applications knowledge for regenerative medicine in the field are explained.