Titlebook: Cell Biology and Translational Medicine, Volume 14; Stem Cells in Lineag Kursad Turksen Book 2021 The Editor(s) (if applicable) and The Aut

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https://doi.org/10.1007/978-94-009-3869-4rview of the catalysis-dependent and independent data emerging on the molecular mechanisms of the functions of AKRBs in different tumor models with an emphasis of the role of these enzymes in chemoresistance, inflammation, oxidative stress and epithelial-to-mesenchymal transition.

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A. S. Ward MS,FRCS,J. M. Cormier MD vivo using induced pluripotent stem cell (iPSC) technology and are discussed here. PD pathophysiology is not faithfully replicated by animal models, and, therefore, nigral dopaminergic neurons generated from iPSC serve as improved human cellular models. With no cure to date and treatments aiming at

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A. S. Ward MS,FRCS,J. M. Cormier MDrreversible organ damage has occurred..Here, we provide an overview of the known effects of LSDs on stem cell function, as well as a synopsis of available stem cell-based cell and gene therapies that have been/are being developed for the treatment of LSDs. We discuss the advantages and disadvantages

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Cell Biology and Translational Medicine, Volume 14Stem Cells in Lineag

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