Titlebook: Cell Adhesion Molecules; Implications in Neur Vladimir Berezin,Peter S. Walmod Book 2014 Springer Science+Business Media New York 2014 cell

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ICAM-5: A Neuronal Dendritic Adhesion Molecule Involved in Immune and Neuronal Functionsructure with nine external immunoglobulin domains followed by a transmembrane and a cytoplasmic domain. The external part binds to β1- and β2-integrins and the matrix protein vitronectin, whereas its transmembrane domain binds to presenilins and the cytoplasmic domain to α-actinin and the ERM family

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New Insights into the Roles of the Contactin Cell Adhesion Molecules in Neural Developmentg roles in the formation and maintenance of the nervous system. CNTN1 and CNTN2 are the prototypical members of the family and have been involved, through .- and .-interactions with distinct cell adhesion molecules, in neural cell migration, axon guidance, and the organization of myelin subdomains.

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The L1 Family of Cell Adhesion Molecules: A Sickening Number of Mutations and Protein Functionsand five fibronectin type III domains. By engaging in many different protein–protein interactions they are involved in a multitude of molecular functions and are important players during the formation and maintenance of metazoan nervous systems. As a result, mutations in L1-type genes cause a great

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Organisation and Control of Neuronal Connectivity and Myelination by Cell Adhesion Molecule Neurofast functions have been described including control of neurite outgrowth, clustering of protein complexes at the axon initial segments as well as at the nodes of Ranvier and axoglial contact formation at paranodal segments. At the molecular level, neurofascin provides a link between extracellular inte

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Roles for DSCAM and DSCAML1 in Central Nervous System Development and Diseasending member of the family was isolated in a positional cloning study that sought to identify genes located on chromosome 21 at the locus 21q22.2–q22.3 that is implicated in the neurological and cardiac phenotypes associated with Down’s syndrome. In ., Dscam proteins are involved in neuronal wiring,

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Neural Cell Adhesion Molecules Belonging to the Family of Leucine-Rich Repeat Proteinstracellular LRRs. These encode cell adhesion molecules (CAMs), proteoglycans, G-protein-coupled receptors, and other types of receptors. Here we give a brief description of 36 proteins with extracellular LRRs that all can be characterized as CAMs or putative CAMs expressed in the nervous system. The

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Thy-1 Modulates Neurological Cell–Cell and Cell–Matrix Interactions Through Multiple Molecular Inter–receptor association triggers neurite retraction and inhibition of axonal growth (. signaling). Although Thy-1 lacks a cytoplasmic domain, it affects multiple intracellular signaling cascades through interaction with a number of molecules within lipid raft microdomains. Improved understanding of ho