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Titlebook: Catalytically Active Nucleic Acids; Harald Seitz,Frank Stahl,Johanna-Gabriela Walter Book 2020 Springer Nature Switzerland AG 2020 RNA G-Q

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書目名稱Catalytically Active Nucleic Acids
編輯Harald Seitz,Frank Stahl,Johanna-Gabriela Walter
視頻videohttp://file.papertrans.cn/223/222489/222489.mp4
概述Highlights fundamental aspects of nucleic acids enzymes.Addresses methods and applications.Discusses challenges in and prospects for nucleic acid enzyme engineering
叢書名稱Advances in Biochemical Engineering/Biotechnology
圖書封面Titlebook: Catalytically Active Nucleic Acids;  Harald Seitz,Frank Stahl,Johanna-Gabriela Walter Book 2020 Springer Nature Switzerland AG 2020 RNA G-Q
描述.This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids’ fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes...After the discovery of natural ribozymes – RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds – numerous artificial ribozymes with altered catalytic activities were produced by .in vitro. and .in vivo. selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat...Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamental
出版日期Book 2020
關(guān)鍵詞RNA G-Quadruplexes; DNAzymes; nucleic acids; Aptazymes; Transcriptome; RNaseP Ribozyme; DNAzyme Engineerin
版次1
doihttps://doi.org/10.1007/978-3-030-29646-9
isbn_softcover978-3-030-29648-3
isbn_ebook978-3-030-29646-9Series ISSN 0724-6145 Series E-ISSN 1616-8542
issn_series 0724-6145
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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What is Life? Open Quantum Systems Approacher hand, the combination of aptamers and DNAzymes has led to the development of aptazymes for specific targets. An up-to-date summary of the most interesting DNAzyme-based assays is presented here. The elaborated systems can be used in medical diagnosis or chemical and biological studies.
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Hemin/G-Quadruplex Horseradish Peroxidase-Mimicking DNAzyme: Principle and Biosensing Application,d easy modification. Considering these remarkable properties, the hemin/G-quadruplex DNAzyme is extensively used in electrochemical, colorimetric, and chemiluminescence sensors and biosensors for detection of various targets.
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Catalytically Active Nucleic Acids978-3-030-29646-9Series ISSN 0724-6145 Series E-ISSN 1616-8542
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