Titlebook: Case-Based Gynecological Oncology; Kavita Singh,Bindiya Gupta Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive l

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Epithelial Ovarian Cancer: High Grade SerousEpithelial ovarian cancer mainly presents in advanced stage. In recent years, treatment has been revolutionized by changes in surgical and medical management, introduction of targeted therapies and biomarker directed therapies. This change in the treatment paradigm has had substantially improved survival statistics.

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Recurrent Ovarian CancerRecurrent ovarian cancer may be sensitive to platinum or platinum resistant. Management includes a combination of chemotherapy and targeted therapy. Secondary debulking surgery can be done in select cases where it is possible to achieve complete cytoreduction..This chapter will discuss clinical scenarios of recurrent ovarian cancer.

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Metastatic Ovarian Canceristochemistry especially using CK7 and CK20 are the most commonly used antigens in differentiating between primary and metastatic ovarian tumours. Genetic testing is crucial for counselling and tailoring management. Treatment is mainly palliative chemotherapy while in select cases metastatectomy or cytoreductive surgery may be useful.

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Borderline Ovarian Tumours: Early and Advance Stage: Serous, Mucinous, Micro Invasive Cancer, Invasi mild nuclear atypia without destructive stromal invasion. These account for 10–15% of all epithelial tumours. The most common subtypes are serous and mucinous tumours. Surgery is the mainstay of management and these are associated with better prognosis than invasive carcinomas.

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