Titlebook: Cardiac Repolarization; Basic Science and Cl Nabil El-Sherif Book 2020 Springer Nature Switzerland AG 2020 Cardiovascular pharmacotherapeut

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The Role of Inflammation and Autoimmunity in Long QT Syndromeically involved in ventricular APD (.), leading to acquired forms of LQTS of autoimmune origin. The most investigated are anti-Ro/SSA antibodies, acting via an inhibition of the human Ether-a-go-go-Related Gene (hERG) potassium channel..To date, the potential impact of inflammatory and autoimmune ch

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Genetics, Molecular Biology, and Emerging Concepts of Early Repolarization SyndromeV. Loss of the AP dome at some epicardial sites but not others creates an epicardial dispersion of repolarization giving rise to phase 2 reentrant extrasystole. Loss of the epicardial AP dome also creates a transmural dispersion of repolarization giving rise to a vulnerable window across the ventric

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Electrocardiographic J Wave and Cardiovascular Risk in the General Populationtype characteristics, which can help in separating ER syndrome from benign patterns of ER. This chapter presents the current knowledge of the prevalence and significance of ECG pattern of ER in general population.

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Pr?vention im Alter: Lohnt sich das noch?tips in favor of the outward flow of positive ions begins the repolarization process. The molecular determinants of these currents are ions passing through a network of ion channels. In this chapter we review the key ion channels that underlie cardiac repolarization and focus on critical potassium i

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