Titlebook: Cardiac Regeneration; Masaki Ieda,Wolfram-Hubertus Zimmermann Book 2017 Springer International Publishing AG 2017 fibroblast.heart repair.

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Direct Cardiac Reprogramming,o far clinically tested adult stem cells seems to be a rare event, and the beneficial effects of these cell-based therapies are likely due to paracrine factors secreted by the transplanted cells. To regenerate cardiac muscle, it is important to first understand the mechanism of cardiac cell fate det

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State of the Art in Cardiomyocyte Transplantation,ost-infarct heart failure. In this chapter, we review the status of preclinical studies of cardiomyocyte transplantation, describe the significant remaining barriers to clinical translation, and consider potential target patient populations and study design for a first-in-human study of PSC-derived

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Stem Cell Transplant Immunology,ind stem cell immunogenicity—including specific cases of embryonic and patient-specific stem cell rejection—is pivotal for researchers to develop more efficient therapeutics. The future of stem cell transplantation research lies in developing techniques that prevent immune recognition of transplante

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Normalization Techniques in Deep Learning regarding epicardium formation, heterogeneity, and its therapeutic potential in heart repair. Moreover, we draw attention to studies focusing on the human epicardium, highlighting new tools that are being developed to promote further insight into the epicardium and its regenerative potential.

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