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Titlebook: Cardiac Metabolism in Health and Disease; Salah Abdel-Aleem,James E. Lowe Book 1998 Springer Science+Business Media Dordrecht 1998 ATP.Gly

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發(fā)表于 2025-3-21 17:58:58 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Cardiac Metabolism in Health and Disease
編輯Salah Abdel-Aleem,James E. Lowe
視頻videohttp://file.papertrans.cn/222/221795/221795.mp4
叢書(shū)名稱Developments in Molecular and Cellular Biochemistry
圖書(shū)封面Titlebook: Cardiac Metabolism in Health and Disease;  Salah Abdel-Aleem,James E. Lowe Book 1998 Springer Science+Business Media Dordrecht 1998 ATP.Gly
描述This special issue of .Molecular and Cellular Biochemistry.contains original research papers as well as invited reviews focusedin the field of cardiac metabolism and its regulation under normal anddisease conditions. These papers cover many areas under intensive andrapid development such as the regulation of fatty acid oxidation inthe heart, the role of cardiac glycogen during ischemia, the role ofCPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy,cardiac protection through regulation of energy production, the roleof fatty acid binding protein under normal and pathologicalconditions, and several other important topics in this area ofresearch. We hope that this special issue of .Molecular andCellular. .Biochemistry. provides an up-to-date source ofinformation for scientists and clinicians interested in the mechanismby which cardiac metabolism is regulated in health and disease and themechanistic relationship between disturbances in cardiac metabolismand the genesis of cardiovascular diseases.
出版日期Book 1998
關(guān)鍵詞ATP; Glycogen; Oxidation; Purine; biochemistry; cardiac function; cardiovascular; metabolism
版次1
doihttps://doi.org/10.1007/978-1-4615-5687-9
isbn_softcover978-1-4613-7603-3
isbn_ebook978-1-4615-5687-9
copyrightSpringer Science+Business Media Dordrecht 1998
The information of publication is updating

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Carnitine deficiency-induced cardiomyopathy,e a major effect on the cardiac contractile function, although substrate oxidation may be altered. However, with longer durations of carnitine deficiency, alterations occur within the heart that may result in impaired contractile performance, particularly at high workloads.At this point, the mechani
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Fatty acid-binding proteins in the heart,unctioning. The low solubility of fatty acids in aqueous solutions impairs their cellular transport. However, cardiac tissue contains several proteins capable of binding fatty acids non-covalently. These fatty acid-binding proteins (FABPs) are thought to facilitate both cellular uptake and intracell
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Metabolic disturbances in diabetic cardiomyopathy,y cardiac myocytes could be the primary injury in the pathogenesis of this specific heart muscle disease. For example, in diabetes, glucose utilization is insignificant, and energy production is shifted almost exclusively towards β-oxidation of free fatty acids (FFA). FFA’s are supplied to cardiac c
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Phospholipase A2-mediated hydrolysis of cardiac phospholipids: The use of molecular and transgenic net degradation of phospholipids and the accumulation of degradation products, such as lysophospholipids and (non-esterified) fatty acids. The derangements in phospholipid metabolism are thought to be involved in the sequence of events leading to irreversible myocardial injury. The net degradation o
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Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development andd intracellularly or by extracellular substrate availability. To determine this, the effect of exogenous L-carnitine on the regulation of carbohydrate and fatty acid metabolism was determined during cardiac stress (hypoxia) and during the postnatal period. The effect of L-carnitine on long chain (pa
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