Titlebook: Cardiac Extracellular Matrix; Fundamental Science Eric G. Schmuck,Peiman Hematti,Amish N. Raval Book 2018 Springer Nature Switzerland AG 2

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Biomechanical Properties and Mechanobiology of Cardiac ECM,ew the mechanobiology of cardiac tissues, i.e., the biomechanical responses at the cellular and tissue level, with an emphasis on the impact on the cardiac ECM. The regulation of cardiac ECM on cell function, which is a new and open area of research, is also briefly discussed. Future investigation i

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Imaging the Cardiac Extracellular Matrix,le noninvasive methods and cellular-scale invasive methods. Noninvasive methods can be used on patients, but only a few are clinically available, and others require further development to be used in the clinic. Invasive methods are the most established and can measure a variety of properties, but th

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Applications of Cardiac Extracellular Matrix in Tissue Engineering and Regenerative Medicine,ardiac regeneration as well as bottom-up and top-down approaches to ECM-based cardiac tissue engineering is discussed. Finally, lingering questions regarding the role of cECM in tissue engineering and regenerative medicine are offered as a catalyst for future research.

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Whole Cardiac Tissue Bioscaffolds,he vascular conduits, injection into parenchyma, or a combination of perfusion and injection. Endothelial cells are often perfused through existing vessel conduits to provide an endothelial lining of the vasculature, with cardiomyocytes and other parenchymal cells injected into the myocardium of dec