Titlebook: Cardiac Bioelectric Therapy; Mechanisms and Pract Igor R. Efimov,Fu Siong Ng,Jacob I. Laughner Book 2021Latest edition Springer Nature Swit

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History of Optical Mappingnter-relationship between different physiological phenomena. This chapter discusses the origins of the use of optical mapping in cardiac research, the process of optical mapping of the heart, and the evolution of dyes and equipment used.

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Bidomain Model of Defibrillationl state of the myocardium, but also to the intrinsic properties of the tissue that lead to destabilization of postshock activations and their degradation into electric turbulence. The complexity of the relationships and dependencies to be teased out and dissected in this quest has been staggering.

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The Role of Microscopic Tissue Structure in Defibrillatione order of few hundred micrometers in length may suffice to interrupt fibrillatory propagation. Overall, the connective tissue network, especially if it becomes more expressed in disease states or during evolving age, plays an important role in defibrillation.

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Virtual Electrode Theory of Pacingon the cardiac bidomain provides a strong and well-validated foundation for our understanding of cardiac pacing, magnetocardiography, and defibrillation, and will help usher in a new era of studies on the interactions between membrane potential, calcium, and mechanical deformation.

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Advanced Three-Dimensional Optical Mappingsensitive dyes and imaging modalities, such as transillumination, have paved the way for novel three-dimensional optical imaging techniques aiming at depth-resolved reconstruction of cardiac electrical activity.

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