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Titlebook: Cancer Therapy; Monoclonal Antibodie Hans G. Beger (Professor of Surgery),Markus Büchle Conference proceedings 1989 Springer-Verlag Berlin

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書目名稱Cancer Therapy
副標(biāo)題Monoclonal Antibodie
編輯Hans G. Beger (Professor of Surgery),Markus Büchle
視頻videohttp://file.papertrans.cn/222/221213/221213.mp4
圖書封面Titlebook: Cancer Therapy; Monoclonal Antibodie Hans G. Beger (Professor of Surgery),Markus Büchle Conference proceedings 1989 Springer-Verlag Berlin
描述A variety of new cancer therapy modalities are discussed and evaluated in this book. It aims to demonstrate that the combination of classical chemo- and radiotherapy with new approaches in the field of immunotherapy can result in an improved treatment modality. Immunotherapy in this context consists of therapy with monoclonal antibodies, hematopoietic growth factors and other lymphokines. Results of early clinical trials with IL-2, GM-CSF and monoclonal antibodies against gastrointestinal tumors and melanoma are included. The progress in regional chemotherapy strategies, for example of the liver, is shown. In addition, the development of new chemotherapeutic agents with a different mode of action as well as better tolerability is presented. The use of hormones, such as LH-RH agonists, allows hormone-dependent tumors such as prostatic and breast cancer to be treated without strong adverse reactions. These recent findings give the reader insight into exciting therapeutic directions made possible by such combined, rather than single, modalities.
出版日期Conference proceedings 1989
關(guān)鍵詞breast cancer; cancer; cancer therapy; chemotherapy; clinical trial; hormones; immunotherapy; liver; melanom
版次1
doihttps://doi.org/10.1007/978-3-642-73721-3
isbn_softcover978-3-642-73723-7
isbn_ebook978-3-642-73721-3
copyrightSpringer-Verlag Berlin Heidelberg 1989
The information of publication is updating

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https://doi.org/10.1007/978-981-19-5570-9lonal antibodies has rapidly led to clinical investigations. Experience with monoclonal antibodies in the treatment of patients with melanoma is limited [4, 9, 10, 12, 13, 17, 19] because only small groups of patients have been treated so far. According to these studies, treatment with ganglioside antibodies appears most promising.
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Mab 17-1A Used for Therapy of Patients with Metastatic Colorectal Carcinomasially on fetal cells. On normal mature cells, TAA might be detected only by highly sensitive techniques or after manipulation of the cell membrane. On malignant cells, TAA are often re-expressed in high concentrations. Such antigens can be exploited not only for diagnostic purposes, but also as targets for immunotherapy.
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Immunotherapy of Malignant Melanomaslonal antibodies has rapidly led to clinical investigations. Experience with monoclonal antibodies in the treatment of patients with melanoma is limited [4, 9, 10, 12, 13, 17, 19] because only small groups of patients have been treated so far. According to these studies, treatment with ganglioside antibodies appears most promising.
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The Role of Interferon in the Management of Patients with Hairy Cell Leukemia and Multiple Myeloma of cancer, particularly since in 1981 highly purified material produced by recombinant DNA technology has become available in addition to natural IFNs [25, 51, 59]. So far, the most impressive clinical results have been achieved in hematologic disorders, especially in hairy cell leukemia [26, 41, 54].
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