Titlebook: Cancer Neuroscience; Moran Amit,Nicole N. Scheff Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spr

Neuropeptides

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Jane Duncan,Bradley W. Griffin,Travis Malone nerves continues to grow, a greater appreciation of the complexity of the tumor microenvironment emerges. Peripheral tumors recruit different branches of the nervous system – sympathetic, parasympathetic, and sensory – each of which impacts disease progression in mechanistically distinct ways. More

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Jane Duncan,Bradley W. Griffin,Travis Maloneome time, but recent research has shed light on the substantial impact of this cross talk in cancer development and progression and the tumor microenvironment. This cross talk is carried out via the paracrine and autocrine release of neurotransmitters and neuropeptides and plays a pivotal role in th

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Elizabeth A. Osborne,Shelby Lundermanevidence reveal a strong impact of stress in the progression of this disease. Moreover, research has shown the potential role of several types of nerve fibers in the bone marrow which can influence cancers in this site. This evidence has already led to the development of new clinical trials that eva

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New Directions in Teaching Theatre Artscells, immune cells, and neurons along with other components (Denton et al., Adv Exp Med Biol 1060:99–114, 2018)). Recent discoveries have shown the key role of stroma-cancer interactions in shaping the tumor microenvironment. For instance, fibroblasts, found and activated in the tumor microenvironm

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https://doi.org/10.1007/978-3-031-13540-8d the biology of nerve-cancer interactions. Growing interest in this area of research can be attributed to the recognition that increased tumor innervation contributes to enhanced tumorigenesis in numerous cancer models and has been clinically linked to more aggressive tumors and worse prognoses. Wh

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https://doi.org/10.1007/978-3-031-13540-8mpt to guess where cancer neuroscience will go, and suggest the steps that might take the field into the next decade. As shown in this volume, this area of investigation is exploding, making this task difficult. Thus, being predictive is a perilous venture as many of the obvious directions are curre

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