Titlebook: Cancer Metastasis Through the Lymphovascular System; Stanley P. Leong,S. David Nathanson,Jonathan S. Za Textbook 2022 The Editor(s) (if ap

一致性

Hallmarks of Cancer: Molecular Underpinningser normal cells, making them self-sustainable, invade and metastasize to distant locations. This chapter provides a brief overview and key concepts on the molecular underpinnings of cancer cells composed of eight hallmarks of cancer and two enabling characteristics.

Tidious

Pathologic Assessment of Systemic or?Distant Metastasis(IHC) stains, and, increasingly, massively parallel sequencing to probe a tumor’s genomic, transcriptomic, and epigenomic landscape. Pathologists integrate these modalities into unified diagnoses that form the basis for patients’ oncologic care.

臨時抱佛腳

Therapy-Induced Dormancy and Residual Diseaseesidual cells during a prolonged dormant period, and eventually recur. In this chapter, we review the clinical evidence suggesting that dormant residual tumors are an important reservoir for tumor recurrence, and then discuss some of the molecular and cellular features of dormant residual tumors.

Exuberance

forebear

Tumor Dormancy and Relapse Regulated by the Extracellular Matrix1 and periostin can accelerate dormant tumor outgrowth. This chapter will give an overview of such studies to elucidate the roles of these ECM proteins, other factors found in ECM, and the mechanical properties of ECM in regulating dormancy and reactivation of disseminated tumor cells.

aplomb

Textbook 2022 lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. .The book begins with a comprehensive overview of the genetic and molecular mec

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Allaberen Ashyralyev,Pavel E. Sobolevskiihelp us further classify tumors based on molecular findings, rather than the traditional, purely histologic findings, which may or may not provide valuable information regarding predictive factors and prognostic information. This chapter goes into detail with examples of several different types of m

歡笑

Allaberen Ashyralyev,Pavel E. Sobolevskiius never-ending topics. Each of them deserves separate in-depth exploration. We hence set out to briefly introduce their basic biological functions, discuss their roles in tumor growth and mechanisms of interaction with tumor cells and among themselves, summarize representative research and mileston

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