Titlebook: Cancer Markers; Diagnostic and Devel Stewart Sell Book 1980 The HUMANA Press Inc. 1980 cancer.carcinogenesis.carcinoma.cell.classification.

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Theoretical and Practical Considerations of the Utility of the Radioimmunoassay for Carcinoembryoni The fact that CEA was absent from corresponding normal adult tissues, but was demonstrated in human embryonic and fetal digestive organs by the immunologic techniques employed in the initial observations, accounts for the designation given the molecule and the hypothesis that the reinitiation of it

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Surface Glycolipid and Glycoprotein Antigens,ese changes determine some of the important properties of cancer cells. These properties include loss of contact inhibition, decrease in cell adhesion, increased growth, prolonged survival, expression of new antigens, and escape from immune destruction by the host. Cell surface carbohydrates are bel

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Lectin Interactions with Normal and Tumor Cells and the Affinity Purification of Tumor Cell Glycoprs, have been isolated from a wide variety of plants and animals (reviewed in Lis and Sharon, 1973; Nicolson, 1974a; Sharon and Lis, 1975; Roth, 1978; Goldstein and Hayes, 1978). Lectin interactions with carbohydrate-containing molecules on cells resemble antibody-antigen reactions, since most lectin

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Transfer RNA and Its By-Products as Tumor Markers,ssenger RNA (mRNA) has only a unitary function, namely, to carry the information from the DNA to the cytoplasm. Transfer RNA, on the other hand, has a large variety of known functions, and others are probably still unrevealed. The function that was discovered first, namely, transporting amino acids

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Circulating Immune Complexes in Cancer,tivity of the assays available (Robins and Baldwin, 1977). Even more pertinent are those tumor markers that are immunogenic in the tumor-bearing individual since their interaction with the immunological network of the host should lead to the induction of specific immune responses. This type of appro

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