Titlebook: Cancer Immunology and Immunotherapy; Glenn Dranoff Book 2011 The Editor(s) (if applicable) and The Author(s), under exclusive license to S

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Book 2011ells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.

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