Titlebook: Cancer Chemoprevention; Volume 1: Promising Gary J. Kelloff,Ernest T. Hawk,Caroline C. Sigman Book 2004 Springer Science+Business Media Ne

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Vasso Zisimopoulou,Panayiotis N. Varelashospholipase A. (PLA.). Free AA can then be metabolized through three major pathways: cyclooxygenase (COX) to produce prostaglandins (PG) and thromboxane, lipoxygenase (LOX) to produce leukotrienes and hydroxy eicosatetraenoic acid (HETES), and cytochrome P-450 to produce epoxyeicosatrienoic acids (

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Gary J. Kelloff,Ernest T. Hawk,Caroline C. SigmanIncludes supplementary material:

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Cancer Drug Discovery and Developmenthttp://image.papertrans.cn/c/image/221068.jpg

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Inducers of Enzymes That Protect Against Carcinogens and Oxidantsotection has been achieved by administering the chemopreventive agent prior to and/or concurrently with the exposure to the carcinogen. Considering this temporal relationship between the administration of anticarcinogen and carcinogen, it seems likely that these agents act at least in part to alter

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