Titlebook: Calcium Homeostasis; Ernesto Carafoli,Joachim Krebs Book 2000 Springer-Verlag Berlin Heidelberg 2000 ATP.Calcium.biochemistry.calcineurin.

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https://doi.org/10.1007/978-3-642-81964-3ependent on changes of the intracellular concentrations of the second messenger Ca.. In this chapter the structural and functional properties of CaMkinases are summarized. The different kinases known to date can be either monospecific for one substrate or multifunctional, recognizing a number of dif

解決

https://doi.org/10.1007/978-3-642-81964-3d a major problem in biology at the molecular level: how are external signals acting on plasma membrane receptors transmitted to the nucleus. The specific inhibition by immunosuppressive drugs, complexed with their binding proteins, of the Ca./ calmodulin-dependent protein phosphatase, calcineurin,

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https://doi.org/10.1007/978-3-642-81964-3sport across intracellular membranes. Coupling of ATP hydrolysis and Ca. transport is based on an intramolecular long-range linkage between ATP hydrolysis within the cytosolic region, and vectorial displacement of bound Ca. within the membrane-bound region of the ATPase. Equilibrium and kinetic meas

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https://doi.org/10.1007/978-3-642-81964-3 has been found not only in all mammalian cells, but also in varieties of invertebrates and in yeast. So far no PMCA genes have been found in bacteria. The biochemical and biophysical properties of the pump have been primarily studied on the enzyme purified from the membrane of the red blood cells b

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https://doi.org/10.1007/978-3-642-81964-3ularly important to excitable tissues. Three homologous exchanger gene products (NCX1, 2, 3) are differently expressed in heart, brain and kidney. Hydropathy analysis has indicated 11 hydrophobic segments with highly conserved regions that have been suggested to play a role in ion transport (α-repea

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Calcium Homeostasis978-3-642-58306-3Series ISSN 1437-7993

amenity

Calcium Homeostasis and Its Evolution, described before a description of the systems in particular classes of organism. The organisms are treated in the sequence: prokaryotes, single-cell eukaryotes and, lastly, multicellular organisms reaching up to man. The importance of local homeostasis in compartments contributing to the whole flow

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Calcium-Binding EGF-like Domains,a number of inherited diseases caused by missense mutations within the domain. It is characterised by six cysteine residues which normally disulphide bond in a 1–3, 2–4, 5–6 pattern and a calcium-binding consensus D/N-x-D/N-E/Q-x.-D/ N*-x.-Y/F (where m and n are variables and * indicates possible β-