Titlebook: Calcium Antagonists; Mechanism of Action Nicholas Sperelakis,James B. Caulfield Book 1984 Martinus Nijhoff Publishing, Boston 1984 calcium

Intentional

META

The Potentially Direct Role of Intracellular Calcium Overload in the Electrophysiology of Cardiac Isnnually in the United States. A substantial fraction of these deaths result from immediate effects of ischemia on the electrophysiological properties of ventricular myocardium. Within the first minute after coronary occlusion, there is a reduction in the resting potential of ischemic cells, together

connoisseur

Mechanisms of the Beneficial Effects of Some Ca2+ Antagonists on the Ca2+-Paradox in Myocardiumentry of Ca. through slow calcium channels (1–3). These agents therefore can be seen to protect myocardium under pathophysiological conditions which are associated with a massive amount of Ca. entry and the occurrence of intracellular Ca. overload. Reperfusion of an isolated rat heart with a medium

EXALT

conceal

CRAMP

結(jié)構(gòu)

Congruous

https://doi.org/10.1007/978-3-642-52615-200 (methoxyverapamil) have been best studied, block Ca channels and thereby reduce I. in cardiac tissue (1–4). The consequences of this action include a depression of the action potential plateau and contraction in ventricular muscle (3,5) as well as a reduction in the sinus rate and a prolongation of conduction time through the AV node (6).

Indecisive

Allodynia