Titlebook: CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential; R.W. Compans,M.D. Cooper,Elisabeth Suri-Payer Book 2005 The Edit

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Friedrich Schreiber,Michael Wolffsohnonse is controlled, such as T cell anergy, apoptosis and immune ignorance. A fourth mechanism of peripheral tolerance is the active suppression by regulatory or suppressor T cells. The existence of suppressor T cells was first described in the early 1970s, but these cells became discredited in the 1

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Friedrich Schreiber,Michael WolffsohnPathogenic CD4. T cells are reactive to the parietal cell autoantigen, H/K ATPase, and are controlled by CD4.CD25. T cells in an immunosuppressive cytokine-independent manner. Comparison of CD4.CD25. T cell-mediated suppression in other autoimmune models shows inconsistencies with respect to require

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Isometric

https://doi.org/10.1007/978-3-322-95593-7even wean off immunosuppressive drugs. An improved understanding of the biology of regulatory T cells will make it possible to replace current induction regimens with those favouring the vaccination and selection of T cells that prevent graft rejection. Once tolerance is established, the continuous

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https://doi.org/10.1007/978-3-322-95593-7 High-dose radio-and/or chemotherapy eradicate the hematopoietic system of the patient and induce sufficient immunosuppression to enable donor stem cell engraftment. The replacement of the recipient’s immune system with that of the donor significantly contributes to the success of this treatment, si

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Gesamtchronologie 1980–1986 und 1987 T cell-mediated dominant control of the immune response not only inhibits the development of autoimmune disease, but also impedes effective immunosurveillance against autologous tumor cells. Attenuation of T. cell-mediated immune suppression can therefore evoke effective tumor immunity in otherwise

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https://doi.org/10.1007/978-3-322-95534-0with regulatory activity have been described in mice and humans, and those within the CD4. subset have been extensively characterized. CD4. Type-1 regulatory T (Tr1) cells produce high levels of IL-10 and mediate IL-10-dependent suppression, whereas the effects of naturally occurring CD4.CD25. Tr ce