Titlebook: Bunyaviridae; Daniel Kolakofsky (Professor of Microbiology) Book 1991 The Editor(s) (if applicable) and The Author(s), under exclusive lic

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,The Bunyaviridae and Their Genetics—An Overview, of the genetic properties of these viruses, the factors determining their pathogenic potential for vertebrates, and their transmissibility by arthropod vectors. Detailed descriptions of the individual members of the Bunyaviridae and their attributes together with comprehensive referencing can be fo

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Vital-Signs

Onerous

Bunyaviridae Genome Structure and Gene Expression,f members it is perhaps not unexpected that within the family there is significant diversity in genome structures and expression strategies. In this chapter we first present an overview of the unifying features as well as the diversity within the family. This will orientate the reader for the more d

GENRE

Bunyavirus RNA Synthesis: Genome Transcription and Replication, (NCs). These are large, possibly helical, structures in which the RNA is complexed with predominantly the viral N protein, with sedimentation constants (S.). Crosse virus (LAC) of 115S (L), 90S (M), and 65S (S) in sucrose gradients. Based on the chemical composition of the virus and the proportion

unstable-angina

Bunyavirus Protein Transport and Assembly, the Golgi region (Murphy et al. 1973). Virions bud into the Golgi cisternae and are then transported and released at the cell surface probably by a vesicular transport process utilizing the exocytic pathway. Before assembly of the virus particles, all structural components including proteins as wel

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Antigenic Variance,nic reactivity (Calisher 1988). Evidence for antigenic variance due to mutations and reassortment in the Bunyaviridae family is great and has been obtained by several different approaches. The main intent of this review, however, is not to discuss all the work that has led to the current proposed cl

Discrete

Pathogenesis, animals. This chapter focuses on the few viruses that are important pathogens . and which have been studied in experimental vertebrate hosts. Particular emphasis is given to the California serogroup since this group of agents has received the most detailed analysis. Several other viruses, such as R