Titlebook: Breast Cancer: Cellular and Molecular Biology; Marc E. Lippman,Robert B. Dickson Book 1988 Kluwer Academic Publishers, Boston 1988 Staging

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Steroid hormone regulation of cultured breast cancer cells,affect mammary tumor cell growth? Cell lines clearly have the advantage of relative cellular homogeneity, reproducibility from one experiment to another, ease of experimental manipulation and an approximately defined medium in which growth can be studied. The word ‘a(chǎn)pproximately’ is used because, al

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0927-3042 logy text- books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre- quently publish good in-depth reviews of cancer topics, and publish

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Olivia Hibbitt,Richard Wade-Martinsst carcinoma has long been recognized to be under endocrine control by steroid hormones. Of particular note are the observations that receptors for estrogens, glucocorticoids, vitamin D metabolites, and progestins contain amino acid sequences that are highly homologous to the erb A oncogene (Chapter by G. Stack, .., this volume).

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