Titlebook: Breast Cancer Research and Treatment; Innovative Concepts Ouissam Al Jarroudi,Khalid El Bairi,Giuseppe Curig Book 2023 The Editor(s) (if ap

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The Global Landscape on the Access to Cancer Medicines for Breast Cancer: The ONCOLLEGE Experience,nd formulate solutions for all patients. In this chapter, we discuss drivers of access to innovation for patients with breast cancer, based on a case study of access to HER2-diagnositcs and therapeutics yielding a global landscape analysis, based on the efforts and expertise of the global collaborative group “ONCOLLEGE”.

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Screening Programs for Breast Cancer: Toward Individualized, Risk-Adapted Strategies of Early Detecives of women found to carry a high-risk mutation (i.e., “cascade testing”) as it is in these individuals for whom such actionable information can result in cancers (and/or cancer deaths) being averted. Moreover, even in the absence of clinical cancer genetics services, as is the case for the immedi

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Mechanisms of Endocrine Resistance in Hormone Receptor-Positive Breast Cancer, anti-estrogen drugs and result in constitutive activation of the receptor, even in the absence of estrogens. Epigenetic changes, such as DNA methylation and histone modifications, can also contribute to ET resistance by altering the expression of genes that are involved in estrogen signaling. Under

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