Titlebook: Breast Cancer Chemosensitivity; Dihua Yu,Mien-Chie Hung Book 2007 The Editor(s) (if applicable) and The Author(s), under exclusive license

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紳士

Integrin-Mediated Adhesion: Tipping the Balance between Chemosensitivity and Chemoresistance,mor progression and metastasis. Integrins cooperate with growth factor receptors to control many cellular functions including proliferation and cell survival. Integrin-mediated adhesion regulates many of the cell cycle checkpoints including activation of cyclin D/cdk4/6 complexes, expression of cycl

sorbitol

Insulin-Like Growth Factors and Breast Cancer Therapy,s or may have utility in combination with other agents. Population, preclinical, and basic data suggest the insulin-like growth factor (IGF) system functions to maintain the malignant phenotype in breast cancer. Since the IGFs act via transmembrane tyrosine kinase receptors, targeting of the key rec

失眠癥

宿醉

Molecular Mechanisms of ErbB2-Mediated Breast Cancer Chemoresistance,. ErbB2 is a receptor tyrosine kinase with intrinsic tyrosine kinase activity. The mammalian EGFR family comprises four receptors (EGFR, ErbB2, ErbB3, and ErbB4), which are derived from a series of gene duplications early in vertebrate evolution and are 40%–45% identical.. ErbB2 is the only EGFR fam

Seminar

Estrogen Receptors in Resistance to Hormone Therapy,unctional receptors. Thus, the ER is a major target for current and developing therapies. Although most ER-positive tumors initially respond to hormonal therapies such as tamoxifen, many tumors will eventually become resistant to tamoxifen induced growth inhibition. This chapter will discuss molecul

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Breast Cancer Chemosensitivity978-0-387-74039-3Series ISSN 0065-2598 Series E-ISSN 2214-8019

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