Titlebook: Breast Cancer; Kelly K. Hunt,Geoffrey L. Robb,Naoto T. Ueno Book 2008Latest edition Springer-Verlag New York 2008 Internist.biopsy.breast

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Radiation Therapy for Early and Advanced Breast Cancer,e cancer, radiation therapy plays a central role in breast conservation therapy. Similarly, for selected patients with locally advanced disease who have a sufficient response to neoadjuvant chemotherapy, regional radiation therapy is an important part of a breast conservation approach. Patients with

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Histopathologic and Molecular Markers of Prognosis and Response to Therapy,ng surgical margin status and lymph node status. Accurate determination of histopathologic or nuclear grade provides valuable additional prognostic information. Three molecular markers are routinely assessed to assist with treatment selection: estrogen and progesterone receptors are measured to dete

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Chemotherapy for Breast Cancer,velopment and use of chemotherapy as adjuvant therapy and for the treatment of metastatic disease. In terms of patient survival, anthracyclinecontaining regimens are superior to non-anthracycline-containing regimens, and regimens containing both an anthracycline and a taxane are superior to regimens

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Endocrine Therapy for Breast Cancer,uable in breast cancer prevention. Endocrine therapy results in palliation of disease in 50–60% of patients with hormone receptor—positive metastatic breast cancer. Alone or combined with chemotherapy, adjuvant endocrine therapy significantly reduces the risk of recurrence and has a favorable impact

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Special Clinical Situations in Patients with Breast Cancer,al spinal cord compression, hypercalcemia, and second primary malignancy. For women diagnosed with breast cancer during pregnancy, modified radical mastectomy with axillary lymph node dissection has been the most common surgical intervention, although breast-conserving surgery may be an option. At M

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R, P, B, C,,diation therapy and systemic therapy can lead to sequelae that necessitate a rehabilitation program. Among the most common sequelae of breast cancer treatment are shoulder dysfunction, pain, and lymphedema. A cancer rehabilitation team can help minimize long-term disability, thereby improving qualit

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M, H, A, B, C, ,e estrogen deficiency for a longer duration than women in the general population. Estrogen deficiency can cause hot flashes, vasomotor instability, genitourinary atrophy, cardiovascular disease, and osteoporosis. Hormone replacement therapy (HRT) is effective in the prevention and treatment of vasom