Titlebook: Brain Hypothermia; Pathology, Pharmacol Nariyuki Hayashi (Professor) Conference proceedings 2000 Springer-Verlag Tokyo 2000 Trauma.brain.br

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Neuroprotective Effect of Mild Hypothermia in Experimental Brain Ischemiage because of its harmful complications and the lack of basic knowledge of its beneficial effects. In 1987, it was shown in animal experiments that lowering brain temperature only by a few degrees Celsius during ischemia could protect central neurons against ischemic damages. Since then, widespread

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Conference proceedings 2000he therapy for critically brain-injured patients and breakthroughs in understanding the pathophysiology of brain damage. The latest concept of brain hypothermia therapy clarifies targets such as brain thermal pooling, masking brain hypoxia associated with catecholamine surge, the metabolic shift fro

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Jinkan Sai M.D.,Joe Ariyama M.D.els and various morphological and functional endpoints emphasize how remarkably effective hypothermia can be in protecting the brain. Importantly, these experimental findings with therapeutic hypothermia have been supported by clinical data where hypothermic protection has been demonstrated in patients with severe brain injury [12,13,42].

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