Titlebook: Brain Dopaminergic Systems: Imaging with Positron Tomography; J. C. Baron,D. Comar,B. Mazoyer Book 1991 Springer Science+Business Media Do

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The Linear Tetrahedral (Solid) Element,drug effects and D2-receptor occupancy are reviewed. In conclusion, methods are now available to determine central dopamine receptor occupancy in relation to pharmacological effects. Such relationships may be useful for optimal clinical monitoring of neuroleptic drugs.

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Radioligands for Dopamine Receptor PET Studies: Benzamides and Ligands for Dopamine D-1 Receptors,tuted benzamides bind with high affinity and selectivity to dopamine D-2 receptors. One of them, the salicylamide [.C]raclopride, has been used extensively for the . characterization of binding to central dopamine D-2 receptors. In addition, several main types of benzamide derivatives with different

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Monoamine Precursors in PET Research- Biochemical Issues and Functional Significance,subsequent intracerebral synthesis of monoamines. The modification of the intracerebral kinetics induced by the action of aromatic Lamino acid decarboxylase (AADC), a nonspecific enzyme which catalyses the decarboxylation of a large number of aromatic L-amino acids, permits the possibility to interp