Titlebook: Bone-Metabolic Functions and Modulators; Felix Bronner,Mary C. Farach-Carson,Helmtrud I. Ro Book 2012 Springer-Verlag London 2012 metaboli

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Bone and the cAMP Signaling Pathway: Emerging Therapeutics,fector termed ROCK (Rho-associated kinase). Once activated by RhoA, ROCK promotes phosphorylation of myosin light chain (MLC), producing increased contractility and stress fiber formation, necessary for motility [25]. In osteoclasts, RhoA is activated by engagement of the αV/β3 integrin receptor and

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Nervous System Diseases, Disorders, and Bone: Emerging Therapeutics and Treatment Options,eleased by osteoclasts), but also by neuronal signals released from the peripheral and central nervous systems. This has created a new field of neuroskeletal biology from which key findings are covered in this chapter.

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Book 2012s. is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson..Other titles in this series:-.Bone Formation.Bone Resorption .Engineering of Functional Skeletal Tissues.Bone and Osteoarthritis.Bone and Cancer.Bone and Development.Bone- Metabolic Func

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Bone-Metabolic Functions and Modulators978-1-4471-2745-1Series ISSN 2199-2436 Series E-ISSN 2199-2444

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Fibres, Whiskers, and Platelets,n calcium homeostasis and bone formation. PTH was discovered in the acid extracts of parathyroid glands because it restored the blood calcium level in the parathyroidectomized dog [24]. The existence of PTHrP and its close resemblance to PTH was first suggested by Fuller Albright in 1941 and later d