Titlebook: Bone marrow stem cell therapy for stroke; Kunlin Jin,Xunming Ji,Qichuan Zhuge Book 2017 Springer Nature Singapore Pte Ltd. 2017 bone marro

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Modification of Bone Marrow Stem Cells for Homing and Survival During Cerebral Ischemia,ansplantation. In this chapter, strategies such as gene modification, hypoxia/growth factor preconditioning, and biomaterial-based methods to improve cell survival and homing are summarized, and the potential strategies for their future application are also discussed.

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Potential Mechanisms of Transplanted Cell-Mediated Recovery After Stroke,ional integration with the existing brain circuitry; (2) neuroprotection through trophic factor secretion; (3) increased formation of new vasculature; (4) structural and functional changes to the brain; and (5) recruitment of endogenous progenitors.