Titlebook: Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach; Francesco Saverio De Ponte Book 2012 Springer-Verlag Italia 20

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Use of Bisphosphonates in Osteoporosis,hate synthase. The major treatment goal for patients with osteoporosis is to prevent fractures by maintaining or increasing bone mineral density and reducing excessive bone turnover. Bisphosphonates are well tolerated, but, in many cases oral dosing options have failed because some patients suffer s

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Biomorphology in BIONJ: Anatomy and Histology,oral mucosal cells with disrupted talin function are unable to form focal adhesions and exhibit spreading defects, whereas cells with vinculin disruption can form focal adhesions but display a reduced ability to spread and an increase in cell motility.

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Etiopathogenesis and Clinical Aspects of BIONJ,ed co-morbid factors for ONJ, as the available data are conflicting and not strong enough to support these conditions as risk factors. The clinical findings in BIONJ patients include the exposure of non-vital, white-yellowish bone tissue surrounded by an inflamed and edematous mucosa in the mouth. T

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Prevention and the Role of the Dentist,lue of biochemical markers of bone activity in predicting the jaw osteonecrosis is also explained. The importance of the strict collaboration between dentist, oncologist, and physician is emphasized, including the need to adopt procedures that avoid unnecessary and invasive dental procedures, optimi

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Conservative Treatment: LASER (Biostimulation and Minimally Invasive Surgical Treatment),the vaporization of necrotic bone until healthy bone is reached. The minimal penetration of the erbium laser (0.1?mm) guarantees safety and allows for precise, minimally invasive surgery, inducing a much lower increase in bone temperature than conventional rotary tools (cold ablation). One undoubted

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Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach

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