Titlebook: Biotechnological Applications of Lipid Microstructures; Bruce Paul Gaber,Joel M. Schnur,Dennis Chapman Book 1988 The Editor(s) (if applica

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Liposome-Encapsulated Hemoglobin: A Synthetic Red Cellment. A chemical engineering scale-up feasibility study has been completed recently. We report here the development of an encapsulation method which produces liters of phospholipid/cholesterol liposomes containing at least 16 g% hemoglobin in a few hours. The 0.2 micron liposomes are produced with a

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Some Structural and Functional Properties of Hemoglobin-Containing Liposomes (Hemosomes), A Potentiaa non-toxic, non-immunogenic red blood cell (RBC) surrogate (1–5), and (ii) they provide a useful RBC model for studying the interaction of Hb with lipid bilayers (6,7). We prepared hemosomes by dispersing various (phospho)lipids in concentrated human RBC lysate, and report here on (i) some morpholo

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Liposome-Based Immunoassays for Detection of Small and Large Moleculesilt by attaching a liposome filled with fluorophores to a recognition unit. The fluorophore, carboxyfluorescein (CF), is encapsulated at a high concentration so that it is self-quenched and exhibits low fluorescence. Upon activation of the recognition unit, the liposome is lysed, the CF is diluted i

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